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High activity of histone deacetylases HDACs has been documented in several types of cancer and may be associated with survival advantage. Bcl-2, generally thought to be attached only to membranes, was in melanocytes localized in the cytosol as well. Double Dip 'er 2. Östergötlands Läns Landsting, Laboratoriemedicinskt centrum, Klinisk patologi och klinisk genetik. Furthermore, NP2 mRNA expression is enhanced in the hippocampal subregions as well as in the MHb after long-term treatment with antidepressant drugs of various monoaminergic profiles, indicating a common mode of action of different antidepressant drugs. After 1 month, histology was evaluated by light microscopy and immunocytochemistry.

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Down-regulation of MOSC2 caused impaired lipid synthesis.

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European Blonde Ambitions 5. In unirradiated control melanocytes, coimmunoprecipitation showed that Bim was sequestered by Mcl-1, which had a pro-survival function. Girls Gone Black 1. The aim of this thesis was to clarify the role of lysosomal membrane permeabilization and lysosomal proteases, cathepsins, in signaling for apoptosis. We demonstrate plasma membrane damage induced by UVA irradiation to be rapidly repaired by lysosomal exocytosis in human keratinocytes.

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